APPLICATION OF NMR IN THE INVESTIGATION OF DYNAMIC TAUTOMERISM OF 4(3H)-QUINAZOLINONE SYSTEM

Authors

My Pham Thi Thanh
Kinh Chu Dinh
Thuy Thanh Thi Thu
Vinh Nguyen Ngoc
Chi Nguyen Thi Phuong

Abstract

Tautomerism of 4(3H)-quinazolinone system with [(2-hydroxyphenyl)methylene]-2-(4oxoquinazolin-3(4H)-yl)acetohydrazide and N’-[(1E)-(4-hydroxy-3-methoxyphenyl)methylene]-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazide as two representative compounds was investigated on the basis of 1H NMR method at coalescence with the help of line formprogramme. The dynamic parameters such as k, Ea, DG*, DH*, DS* were fully calculated with high reliability.

Publication Date

11-22-2017

Recommended Citation

Thi Thanh, My Pham; Dinh, Kinh Chu; Thi Thu, Thuy Thanh; Ngoc, Vinh Nguyen; and Thi Phuong, Chi Nguyen (2017) "APPLICATION OF NMR IN THE INVESTIGATION OF DYNAMIC TAUTOMERISM OF 4(3H)-QUINAZOLINONE SYSTEM," ASEAN Journal on Science and Technology for Development: Vol. 25: No. 2, Article 28.
DOI: https://doi.org/10.29037/ajstd.275
Available at: https://ajstd.ubd.edu.bn/journal/vol25/iss2/28